Australian Phenomics Facility

The Australian Phenomics Facility (APF) is a specialised facility for developing, characterising and archiving mouse models of human disease. APF has an open access policy and supports research programmes for research groups and companies around Australia and internationally. The ambition of APF is to generate a steady flow of fundamental discoveries of mammalian physiological function through the use of mouse models, and to facilitate the translation of these discoveries into medical advisories or new health treatments for humans. The APF has for ten years been building collections of variant mice. APF has the capacity to provide the scale of operation necessary to perform large-scale and in-depth screening for new phenotypes upon which researchers can base ongoing investigative experiments. The key has been advances in next generation sequencing and this has accelerated our ability to identify causative gene functions related to particular disease in both humans and mice. This is making available a range of possible gene associations with human disease to study and understand. From this will flow a number of more detailed investigations and approaches for improved personal medicine. The APF has a strong genomics and bioinformatics capability focused on mouse single nucleotide polymorphism (SNP) detection and making the biological association with probable human gene disease traits. The goal is to firstly derive the individual patterns of causation and then look to extend this across the population and better understand cohort differences and responses. In addition to its role as a research facility the APF provides the administrative and operations function for the Australian Phenomics Network (APN). APN is funded by Commonwealth, State and institutional funding to provide infrastructure and expertise for medical research. The 12 partners to the network provide a wide range of resources and services to the research community and enable Australian researchers streamlined access to the data and models generated from international consortium projects.
Type
Party
Party Type
Group
Access Privileges
Phenomics
Title
Australian Phenomics Facility
Brief Description
The Australian Phenomics Facility (APF) is a specialised facility for developing, characterising and archiving mouse models of human disease. APF has an open access policy and supports research programmes for research groups and companies around Australia and internationally. In addition to the mouse model services, the APF provides a full genomic and bioinformatic service provided in partnership with AGRF.
Full Description
The Australian Phenomics Facility (APF) is a specialised facility for developing, characterising and archiving mouse models of human disease. APF has an open access policy and supports research programmes for research groups and companies around Australia and internationally. The ambition of APF is to generate a steady flow of fundamental discoveries of mammalian physiological function through the use of mouse models, and to facilitate the translation of these discoveries into medical advisories or new health treatments for humans. The APF has for ten years been building collections of variant mice. APF has the capacity to provide the scale of operation necessary to perform large-scale and in-depth screening for new phenotypes upon which researchers can base ongoing investigative experiments. The key has been advances in next generation sequencing and this has accelerated our ability to identify causative gene functions related to particular disease in both humans and mice. This is making available a range of possible gene associations with human disease to study and understand. From this will flow a number of more detailed investigations and approaches for improved personal medicine. The APF has a strong genomics and bioinformatics capability focused on mouse single nucleotide polymorphism (SNP) detection and making the biological association with probable human gene disease traits. The goal is to firstly derive the individual patterns of causation and then look to extend this across the population and better understand cohort differences and responses. In addition to its role as a research facility the APF provides the administrative and operations function for the Australian Phenomics Network (APN). APN is funded by Commonwealth, State and institutional funding to provide infrastructure and expertise for medical research. The 12 partners to the network provide a wide range of resources and services to the research community and enable Australian researchers streamlined access to the data and models generated from international consortium projects.
Contact Email
contact@australianphenomics.org.au
Contact Address
117 Garran Road Hugh Ennor Building Acton ACT 2601, Australia
Contact Phone Number
+61 2 6125 1329
Contact Fax Number
+61 2 6125 1381
Website Address
http://apf.anu.edu.au/
Fields of Research
110706 - Immunogenetics (incl. Genetic Immunology)
Keywords
Phenomics
Status: Published
Published to:
  • Australian National University
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